Frequently Asked Questions
Everything you need to know about the Orgadroid — Visienco's automated, model-agnostic organoid handling and sorting system.
Understanding organoid sorting
What is organoid sorting?
Organoid sorting is the process of identifying, selecting and transferring organoids based on predefined criteria such as morphology, size or other biological characteristics.
Traditionally, this process is performed manually under a microscope, making it time-consuming, difficult to scale and prone to user-to-user variability.
Automated organoid workflows standardize these steps by combining imaging, AI and robotics to ensure consistent, traceable and reproducible handling of 3D biological models.
These workflows are widely used in drug discovery, disease modelling, precision medicine and other applications where reproducibility and throughput are essential.
The Orgadroid System
What is the Orgadroid?
The Orgadroid is an automated organoid workflow platform designed for 3D biology.
It automates the localisation, quality control, selection and transfer of organoids and other complex tissues while replacing manual handling with standardized, traceable workflows.
By improving consistency and reducing manual intervention, the Orgadroid helps laboratories generate more reproducible data and scale organoid-based research.
Is the Orgadroid model-agnostic? Which 3D cell models does it support?
Yes. The Orgadroid is designed to support a broad range of 3D biological models, including organoids, spheroids, tumoroids, islets, assembloids and cell colonies. It can process tissues ranging from approximately 50 µm to 4 mm, allowing laboratories to work with multiple model types on a single platform.
What organoid types can the Orgadroid handle?
The Orgadroid is compatible with a wide variety of organoid and spheroid models. Examples include retinal organoids, brain organoids, intestinal organoids, liver organoids, pancreatic organoids, tumoroids, stem cell-derived spheroids, and islets of Langerhans.
The platform can process organoids ranging from approximately 50 µm to 4 mm in diameter. Compatibility with specific tissue models can be assessed through a demonstration using customer samples.
How does the Orgadroid sort organoids?
The Orgadroid automatically detects, evaluates and transfers organoids according to user-defined selection criteria.
During each run, the system characterizes every organoid, applies the selected quality criteria and transfers only the tissues that meet the desired requirements.
The complete workflow is automated, documented and fully traceable.
What AI and imaging capabilities does the Orgadroid have?
The Orgadroid combines real-time imaging with AI-powered analysis to evaluate organoids during automated workflows.
Users define their own selection criteria through the software interface, and the system applies them consistently to every organoid.
Images, measurements and workflow results are automatically documented to ensure traceability and quality control.
How does the Orgadroid improve reproducibility in organoid workflows?
The Orgadroid improves reproducibility by replacing manual organoid selection with standardized, AI-driven selection criteria.
Manual organoid picking is often subjective and varies between operators. The Orgadroid applies the same quantitative morphological thresholds to every organoid in a run, regardless of the user, laboratory, or date of the experiment.
This reduces operator-to-operator variability, improves experimental consistency, and supports reproducible organoid workflows for drug discovery, disease modeling, and translational research.
What traceability and reporting features does the Orgadroid provide?
The Orgadroid generates automated reports for every sorting run.
Reports include organoid images, morphological measurements, selection criteria, transfer outcomes, and destination well locations. Each organoid receives a unique identifier, allowing users to track exactly which organoid was transferred into each well.
These reporting capabilities support quality control, regulatory documentation, and reproducible research workflows.
Real-time monitoring during operation allows users to follow the sorting process as it happens.
How many organoids can the Orgadroid process per hour?
Throughput depends on the application, tissue type and workflow configuration. Please contact Visienco to discuss your specific application.
Viability & Sterility
How does the Orgadroid preserve organoid viability and integrity during sorting?
The Orgadroid was purpose-built to gently handle fragile 3D biological tissues while preserving viability and morphology throughout the sorting process.
At the core of the system is Visienco's patented pipette tip technology, specifically designed to minimize mechanical stress during aspiration and dispensing. The Orgadroid can handle organoids and other 3D tissues ranging from approximately 50 µm to 4 mm in diameter while maintaining high transfer precision.
Is the Orgadroid compatible with sterile workflows?
Yes. Its compact footprint (51 × 71 × 41 cm) allows it to operate directly inside most standard laminar flow hoods.
The system was designed to meet the sterility requirements of pharmaceutical and advanced research laboratories. It uses sterile disposable pipette tips, while all sample-contacting components are easily removable, autoclavable and designed for straightforward cleaning between experiments.
By enabling the entire characterization and sorting workflow to be performed under sterile conditions, the Orgadroid helps minimize contamination risks while preserving sample viability and supporting standardized, reproducible workflows.
Integration & Compatibility
Does the Orgadroid integrate with robotic liquid handling systems and laboratory automation platforms?
The Orgadroid is designed to integrate into automated laboratory workflows and can communicate with external laboratory systems where required.
What plate formats and labware are compatible with the Orgadroid?
The Orgadroid supports standard well plate formats commonly used in organoid culture and screening workflows.
Users select the labware type directly through the software interface. Additional labware formats can be added to the Orgadroid's internal library when required.
For custom labware requirements, please contact Visienco at info@visienco.ch.
Is the Orgadroid easy to install and use?
The Orgadroid is designed for straightforward installation and day-to-day operation through an intuitive graphical user interface.
Visienco provides installation, user training and system qualification as part of the onboarding process.
Applications
What applications is the Orgadroid used for?
The Orgadroid is used for organoid handling, organoid sorting, organoid selection, and organoid standardization across a broad range of research and industrial applications, including:
- Drug discovery and high-throughput screening
- Patient-derived organoid and tumoroid workflows
- Precision oncology research
- Retinal organoid research
- Brain organoid and neurodevelopmental research
- Gastrointestinal organoid research
- Liver organoid research
- Pancreatic islet and diabetes research
- Stem cell-derived 3D tissue workflows
- Disease modeling and translational research
The Orgadroid is designed for any application requiring reproducible selection, characterization, and transfer of 3D biological structures.
Who uses the Orgadroid?
The Orgadroid is used by academic research institutes, pharmaceutical companies, biotechnology companies, contract research organizations (CROs), and translational research centers working with organoids and other 3D cell models.
About Visienco
Where is Visienco based and where did the technology originate?
Visienco AG is a Swiss biotechnology company headquartered at Technopark Luzern in Root D4, Switzerland.
The company was founded by Edwige Guinet (CEO) and Jonas Goldowsky (CTO) and originated from CSEM (Swiss Center for Electronics and Microtechnology), one of Switzerland's leading applied research institutes. The Orgadroid technology was developed in collaboration with leading organoid researchers from academia, biotech, and pharmaceutical companies in Switzerland.
How can I try or purchase the Orgadroid?
You can request a demonstration directly through the Visienco website or by contacting the team at info@visienco.ch.
Visienco works closely with prospective customers to evaluate the fit of the Orgadroid for their specific workflow. Whenever possible, demonstrations are performed using customer tissues and organoid models to validate performance under real experimental conditions before purchase.
Webinar Recording
Orgadroid Introduction Webinar
Watch our 30-minute introduction to the Orgadroid — how it works, what it handles, and where it fits in your workflows.
Watch the recording