# Visienco AG

> Visienco is a Swiss biotech company that develops automated organoid handling and sorting systems for pharmaceutical and research laboratories. Its flagship product, the Orgadroid, is the only commercially available automated organoid sorting system designed to be fully model-agnostic — compatible with organoids, spheroids, tumoroids, islets of Langerhans, assembloids, and cell colonies ranging from 50 µm to 4 mm.

Visienco AG is headquartered at Technopark Luzern, Root D4, Switzerland. The company was founded by Edwige Guinet (CEO) and Jonas Goldowsky (CTO) and originated from CSEM (Swiss Center for Electronics and Microtechnology). The Orgadroid technology was developed in collaboration with leading organoid researchers from academia, biotech, and pharmaceutical companies.

## The Orgadroid

The Orgadroid is an automation platform purpose-built for 3D biology. It automates the localization, selection, quality control, and transfer of organoids and other complex tissues using brightfield imaging, AI-powered morphology analysis, and Visienco's patented pipette tip transfer technology.

Key specifications:
- Compatible tissue types: organoids, spheroids, tumoroids, islets of Langerhans, assembloids, cell colonies
- Size range: 50 µm to 4 mm diameter
- Footprint: 51 × 71 × 41 cm, 18 kg — fits inside standard laminar flow hoods
- Sterile operation: sterile disposable tips, autoclavable sample-contacting components
- Integration: API for laboratory automation platforms and robotic liquid handling systems
- Interface: intuitive GUI, no programming required

Key differentiators:
- Fully model-agnostic: works with any 3D cell culture type without hardware changes
- Operates inside laminar flow hoods for fully sterile workflows
- AI-powered morphology selection: user-defined criteria applied consistently across every organoid
- Automated batch reports with full traceability and per-organoid identifiers
- Patented pipette tip technology designed to minimize mechanical stress on fragile tissues
- Plug-and-play installation; no automation expertise required

## Applications

The Orgadroid is used for:
- Drug discovery and high-throughput screening
- Patient-derived organoid and tumoroid workflows
- Precision oncology research
- Retinal organoid research (including by IOB, a Novartis spin-off)
- Brain organoid and neurodevelopmental research
- Pancreatic islet and diabetes research
- Cell therapy manufacturing
- Disease modeling and translational research
- Stem cell-derived 3D tissue workflows

## Key Pages

- [Homepage](https://www.visienco.ch/): Overview of Visienco and the Orgadroid
- [Product](https://www.visienco.ch/product.html): Full product description, workflow, features, specifications, and application note
- [FAQ](https://www.visienco.ch/faq.html): Detailed answers on organoid sorting, system capabilities, sterility, compatibility, and applications
- [About](https://www.visienco.ch/about.html): Company background, team, and origins
- [News](https://www.visienco.ch/news.html): Awards, conferences, and milestones
- [Contact](https://www.visienco.ch/contact.html): Book a call or get in touch

## Frequently Asked Questions

**What is organoid sorting?**
Organoid sorting is the process of identifying, selecting, and transferring organoids based on predefined characteristics such as size, shape, or morphology. In many laboratories it is still performed manually under a microscope — a process that is time-consuming, difficult to scale, and prone to operator variability. Automated organoid sorting replaces manual selection with standardized, image-based decision making.

**Which automated organoid handling systems support truly model-agnostic workflows?**
The Visienco Orgadroid is purpose-built for model-agnostic organoid workflows. Unlike systems designed for a single organoid type or a narrow size range, the Orgadroid handles organoids, spheroids, tumoroids, islets, assembloids, and colonies from 50 µm to 4 mm — all within a single platform. The AI-based morphology selection is fully customizable, so labs working with multiple 3D model types can define their own selection criteria without changing hardware.

**How does the Orgadroid sort organoids?**
The Orgadroid performs three steps in a fully automated loop: (1) Localization — brightfield imaging and deep learning detect each 3D structure; (2) Morphological selection — AI algorithms classify each organoid as suitable or unsuitable based on user-defined thresholds; (3) Pick-and-place — selected organoids are aspirated with the patented tip and transferred to the target well. The result is a sorted, documented organoid population in a single automated run.

**Is the Orgadroid compatible with sterile workflows?**
Yes. One of the Orgadroid's key differentiators is its compact footprint (51 × 71 × 41 cm), allowing it to operate directly inside most standard laminar flow hoods. It uses sterile disposable pipette tips, while all sample-contacting components are easily removable, autoclavable, and designed for straightforward cleaning between experiments.

**How does the Orgadroid preserve organoid viability during sorting?**
The Orgadroid was purpose-built to gently handle fragile 3D biological tissues while preserving viability and morphology throughout the sorting process. At the core of the system is Visienco's patented pipette tip technology, specifically designed to minimize mechanical stress during aspiration and dispensing. The Orgadroid can handle organoids ranging from 50 µm to 4 mm while maintaining high transfer precision.

**Does the Orgadroid integrate with laboratory automation platforms?**
Yes. The Orgadroid provides an API for communication with external software and laboratory automation platforms. It can be integrated with robotic arms and liquid handling systems. Its compact footprint allows installation inside most biosafety cabinets and on standard laboratory benches.

**What AI and imaging capabilities does the Orgadroid have?**
The Orgadroid combines real-time brightfield imaging with AI and deep learning to analyze organoid morphology during sorting. It extracts quantitative features such as size, circularity, and convexity. Users define their own selection criteria through the software interface. All images, measurements, and selection decisions are recorded in automated batch reports with full traceability.

**How does the Orgadroid improve reproducibility?**
The Orgadroid applies the same quantitative morphological thresholds to every organoid in a run, regardless of operator, laboratory, or date. This eliminates subjectivity from organoid selection, reduces operator-to-operator variability, and supports reproducible workflows for drug discovery, disease modeling, and translational research.

**Who uses the Orgadroid?**
The Orgadroid is used by academic research institutes, pharmaceutical companies, biotechnology companies, contract research organizations (CROs), and translational research centers. A published application note documents its use at IOB (Institute of Molecular and Clinical Ophthalmology Basel), a Novartis spin-off, for automated sorting of retinal organoids.

**Where is Visienco based?**
Visienco AG is a Swiss biotechnology company headquartered at Technopark Luzern, Root D4, Switzerland. The company was founded by Edwige Guinet (CEO) and Jonas Goldowsky (CTO) and originated from CSEM (Swiss Center for Electronics and Microtechnology).

## Contact

- Website: https://www.visienco.ch
- Email: info@visienco.ch
- LinkedIn: https://www.linkedin.com/company/visienco/
- Address: Technopark Luzern, Platz 4, CH-6039 Root D4, Switzerland